BDBM50520854 CHEMBL4521651
SMILES: COc1ccc(Oc2nc(Nc3ccc(F)cc3)ncc2NC(=O)c2cc(OC)cc(OC)c2)cc1
InChI Key: InChIKey=JQKLMQRMYZFPTG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50520854 (CHEMBL4521651) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST) Curated by ChEMBL | Assay Description Inhibition of human DAPK1 (1 to 363 residues) using KKLNRTLSFAEPG as substrate after 120 mins in presence of 10 uM [gamma-33P]-ATP by filtration meth... | Eur J Med Chem 162: 161-175 (2019) Article DOI: 10.1016/j.ejmech.2018.10.057 | |||||||||||
More data for this Ligand-Target Pair |