BDBM50521287 CHEMBL4448132

SMILES: CCOC(=O)Nc1ccc(cc1NC(=O)OCC)N(CC#C)Cc1ccc(F)cc1

InChI Key: InChIKey=IXCVFHVYOARRRS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50521287 (CHEMBL4448132) Show SMILES CCOC(=O)Nc1ccc(cc1NC(=O)OCC)N(CC#C)Cc1ccc(F)cc1 Show InChI InChI=1S/C22H24FN3O4/c1-4-13-26(15-16-7-9-17(23)10-8-16)18-11-12-19(24-21(27)29-5-2)20(14-18)25-22(28)30-6-3/h1,7-12,14H,5-6,13,15H2,2-3H3,(H,24,27)(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	890	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of human homomeric KCNQ4 expressed in CHOK1 cells at -10 mV by whole cell patch clamp assay				ACS Med Chem Lett 10: 27-33 (2019) Article DOI: 10.1021/acsmedchemlett.8b00315
					More data for this Ligand-Target Pair