BDBM50521964 CHEMBL4563335

SMILES: CCc1cc(C(O)=O)c2c(nn(-c3ccc(Cl)cc3)c2n1)C(C)C

InChI Key: InChIKey=QYEUBDZPTZNDEF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50521964 (CHEMBL4563335) Show SMILES CCc1cc(C(O)=O)c2c(nn(-c3ccc(Cl)cc3)c2n1)C(C)C Show InChI InChI=1S/C18H18ClN3O2/c1-4-12-9-14(18(23)24)15-16(10(2)3)21-22(17(15)20-12)13-7-5-11(19)6-8-13/h5-10H,4H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Transactivation of human GAL4-fused PPARalpha LBD expressed in human HepG2 cells after 24 hrs by renilla luciferase reporter gene assay				Bioorg Med Chem Lett 29: 2124-2128 (2019) Article DOI: 10.1016/j.bmcl.2019.06.062
					More data for this Ligand-Target Pair