null

SMILES: CCOc1ccccc1N1CCN(CN2C(=O)c3c(C)n(c(C)c3C2=O)-c2ccccc2)CC1

InChI Key: InChIKey=SEZMUHRGPNOBDH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50522041 (CHEMBL4537150) Show SMILES CCOc1ccccc1N1CCN(CN2C(=O)c3c(C)n(c(C)c3C2=O)-c2ccccc2)CC1 Show InChI InChI=1S/C27H30N4O3/c1-4-34-23-13-9-8-12-22(23)29-16-14-28(15-17-29)18-30-26(32)24-19(2)31(20(3)25(24)27(30)33)21-10-6-5-7-11-21/h5-13H,4,14-18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw Medical University Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) assessed as suppression of PGG2 conversion to PGH2 incubated fro 2 mins by TMPD based colorimetric assay				Bioorg Med Chem 27: 3918-3928 (2019) Article DOI: 10.1016/j.bmc.2019.07.033 BindingDB Entry DOI: 10.7270/Q2B56P4S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50522041 (CHEMBL4537150) Show SMILES CCOc1ccccc1N1CCN(CN2C(=O)c3c(C)n(c(C)c3C2=O)-c2ccccc2)CC1 Show InChI InChI=1S/C27H30N4O3/c1-4-34-23-13-9-8-12-22(23)29-16-14-28(15-17-29)18-30-26(32)24-19(2)31(20(3)25(24)27(30)33)21-10-6-5-7-11-21/h5-13H,4,14-18H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw Medical University Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin) assessed as suppression of PGG2 conversion to PGH2 incubated fro 2 mins by TMPD based colorimetric assay				Bioorg Med Chem 27: 3918-3928 (2019) Article DOI: 10.1016/j.bmc.2019.07.033 BindingDB Entry DOI: 10.7270/Q2B56P4S
					More data for this Ligand-Target Pair