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SMILES: CC1(C)N=C(C2CCCCC2)c2ccc(cc2N(c2ccc(CCCN)cc2)C1=O)C#N

InChI Key: InChIKey=VFQUTKLPFLZUST-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Parathyroid hormone/parathyroid hormone-related peptide receptor


(Homo sapiens (Human))		BDBM50522127
PNG
(CHEMBL4453102)
Show SMILES CC1(C)N=C(C2CCCCC2)c2ccc(cc2N(c2ccc(CCCN)cc2)C1=O)C#N |t:3|
Show InChI InChI=1S/C27H32N4O/c1-27(2)26(32)31(22-13-10-19(11-14-22)7-6-16-28)24-17-20(18-29)12-15-23(24)25(30-27)21-8-4-3-5-9-21/h10-15,17,21H,3-9,16,28H2,1-2H3
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MMDB

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PC cid
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n/an/a 7.60E+3n/an/an/an/an/an/a



Daiichi Sankyo Co, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human PTHR1 expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-induced cAMP ac...

Bioorg Med Chem Lett 29: 2613-2616 (2019)


Article DOI: 10.1016/j.bmcl.2019.07.052
BindingDB Entry DOI: 10.7270/Q2XW4P6F
More data for this
Ligand-Target Pair