BDBM50522199 CHEMBL4564613

SMILES: Cc1ccccc1NC(=O)CSCn1[nH]nc2c1nc(Cc1ccc(F)cc1)nc2=O

InChI Key: InChIKey=XIGPSUPPWIULRT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine-cytidine kinase 2 (Homo sapiens)	BDBM50522199 (CHEMBL4564613) Show SMILES Cc1ccccc1NC(=O)CSCn1[nH]nc2c1nc(Cc1ccc(F)cc1)nc2=O Show InChI InChI=1S/C21H19FN6O2S/c1-13-4-2-3-5-16(13)23-18(29)11-31-12-28-20-19(26-27-28)21(30)25-17(24-20)10-14-6-8-15(22)9-7-14/h2-9,27H,10-12H2,1H3,(H,23,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.37E+5	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged human UCK2 expressed in Escherichia coli BL21(DE3) cells incubated for 15 mins before ATP addition and measure...				Bioorg Med Chem Lett 29: 2559-2564 (2019) Article DOI: 10.1016/j.bmcl.2019.08.010
					More data for this Ligand-Target Pair