BDBM50522200 CHEMBL1514618

SMILES: CC(C)(C)c1ccc(cc1)-c1nc(SCC(=O)Nc2ccc(Cl)cc2)[nH]c(=O)c1C#N

InChI Key: InChIKey=PEVUZESHWIMPAL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine-cytidine kinase 2 (Homo sapiens)	BDBM50522200 (CHEMBL1514618) Show SMILES CC(C)(C)c1ccc(cc1)-c1nc(SCC(=O)Nc2ccc(Cl)cc2)[nH]c(=O)c1C#N Show InChI InChI=1S/C23H21ClN4O2S/c1-23(2,3)15-6-4-14(5-7-15)20-18(12-25)21(30)28-22(27-20)31-13-19(29)26-17-10-8-16(24)9-11-17/h4-11H,13H2,1-3H3,(H,26,29)(H,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged human UCK2 expressed in Escherichia coli BL21(DE3) cells incubated for 15 mins before ATP addition and measure...				Bioorg Med Chem Lett 29: 2559-2564 (2019) Article DOI: 10.1016/j.bmcl.2019.08.010
					More data for this Ligand-Target Pair