BDBM50522201 CHEMBL4588628

SMILES: Cc1cccc2Cc3c(Oc12)nc(nc3SCC(=O)Nc1cccc(c1)C(O)=O)-c1ccccc1

InChI Key: InChIKey=XFGJSMZOKNVCKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine-cytidine kinase 2 (Homo sapiens)	BDBM50522201 (CHEMBL4588628) Show SMILES Cc1cccc2Cc3c(Oc12)nc(nc3SCC(=O)Nc1cccc(c1)C(O)=O)-c1ccccc1 Show InChI InChI=1S/C27H21N3O4S/c1-16-7-5-10-18-14-21-25(34-23(16)18)29-24(17-8-3-2-4-9-17)30-26(21)35-15-22(31)28-20-12-6-11-19(13-20)27(32)33/h2-13H,14-15H2,1H3,(H,28,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged human UCK2 expressed in Escherichia coli BL21(DE3) cells incubated for 15 mins before ATP addition and measure...				Bioorg Med Chem Lett 29: 2559-2564 (2019) Article DOI: 10.1016/j.bmcl.2019.08.010
					More data for this Ligand-Target Pair