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BDBM50522202 CHEMBL4457001

SMILES: OC(=O)c1cccc(NC(=O)CSc2nc(nc3Oc4ccccc4Cc23)-c2ccc(O)cc2)c1

InChI Key: InChIKey=BKAGEUOQPPPEFO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522202   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uridine-cytidine kinase 2


(Homo sapiens)		BDBM50522202
PNG
(CHEMBL4457001)
Show SMILES OC(=O)c1cccc(NC(=O)CSc2nc(nc3Oc4ccccc4Cc23)-c2ccc(O)cc2)c1
Show InChI InChI=1S/C26H19N3O5S/c30-19-10-8-15(9-11-19)23-28-24-20(13-16-4-1-2-7-21(16)34-24)25(29-23)35-14-22(31)27-18-6-3-5-17(12-18)26(32)33/h1-12,30H,13-14H2,(H,27,31)(H,32,33)
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PC cid
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Article
PubMed
n/an/a 1.66E+5n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of C-terminally His6-tagged human UCK2 expressed in Escherichia coli BL21(DE3) cells incubated for 15 mins before ATP addition and measure...

Bioorg Med Chem Lett 29: 2559-2564 (2019)


Article DOI: 10.1016/j.bmcl.2019.08.010
More data for this
Ligand-Target Pair