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BDBM50523307 CHEMBL4466141

SMILES: COc1ccc(NCc2ccc(OC)c(c2)-c2cccc(Cl)c2)cc1

InChI Key: InChIKey=YPHCBOOVOVVYEG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523307   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50523307
PNG
(CHEMBL4466141)
Show SMILES COc1ccc(NCc2ccc(OC)c(c2)-c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C21H20ClNO2/c1-24-19-9-7-18(8-10-19)23-14-15-6-11-21(25-2)20(12-15)16-4-3-5-17(22)13-16/h3-13,23H,14H2,1-2H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Southern Medical University

Curated by ChEMBL


Assay Description
Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b...

Eur J Med Chem 168: 221-231 (2019)


Article DOI: 10.1016/j.ejmech.2019.02.026
More data for this
Ligand-Target Pair