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BDBM50523308 CHEMBL4535802

SMILES: COc1ccc(CNc2cccc(c2)N(C)C)cc1-c1cccc(Cl)c1

InChI Key: InChIKey=GAGKHFYWMJLTGZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523308   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50523308
PNG
(CHEMBL4535802)
Show SMILES COc1ccc(CNc2cccc(c2)N(C)C)cc1-c1cccc(Cl)c1
Show InChI InChI=1S/C22H23ClN2O/c1-25(2)20-9-5-8-19(14-20)24-15-16-10-11-22(26-3)21(12-16)17-6-4-7-18(23)13-17/h4-14,24H,15H2,1-3H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Southern Medical University

Curated by ChEMBL


Assay Description
Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b...

Eur J Med Chem 168: 221-231 (2019)


Article DOI: 10.1016/j.ejmech.2019.02.026
More data for this
Ligand-Target Pair