BDBM50523312 CHEMBL4520930

SMILES: COc1ccc(CNc2cccnc2)cc1-c1cccc(Cl)c1

InChI Key: InChIKey=HMLQGSOASZZTCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50523312 (CHEMBL4520930) Show SMILES COc1ccc(CNc2cccnc2)cc1-c1cccc(Cl)c1 Show InChI InChI=1S/C19H17ClN2O/c1-23-19-8-7-14(12-22-17-6-3-9-21-13-17)10-18(19)15-4-2-5-16(20)11-15/h2-11,13,22H,12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Medical University Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b...				Eur J Med Chem 168: 221-231 (2019) Article DOI: 10.1016/j.ejmech.2019.02.026
					More data for this Ligand-Target Pair