BDBM50523322 CHEMBL4546037

SMILES: COc1cccc(c1)-c1cc(CNc2cccnc2)ccc1OC

InChI Key: InChIKey=SMOQEMJBMHVCNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50523322 (CHEMBL4546037) Show SMILES COc1cccc(c1)-c1cc(CNc2cccnc2)ccc1OC Show InChI InChI=1S/C20H20N2O2/c1-23-18-7-3-5-16(12-18)19-11-15(8-9-20(19)24-2)13-22-17-6-4-10-21-14-17/h3-12,14,22H,13H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Southern Medical University Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b...				Eur J Med Chem 168: 221-231 (2019) Article DOI: 10.1016/j.ejmech.2019.02.026
					More data for this Ligand-Target Pair