BDBM50523817 CHEMBL4452454

SMILES: [O-][N+](=O)c1ccc2NC(=O)C(=Cc3ccncc3)c2c1

InChI Key: InChIKey=MOVFFFNGOAJMRV-GHXNOFRVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50523817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50523817 (CHEMBL4452454) Show SMILES [O-][N+](=O)c1ccc2NC(=O)C(=Cc3ccncc3)c2c1 Show InChI InChI=1S/C14H9N3O3/c18-14-12(7-9-3-5-15-6-4-9)11-8-10(17(19)20)1-2-13(11)16-14/h1-8H,(H,16,18)/b12-7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of recombinant human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured after 60 mins by ADP-Glo luminescence assay				Bioorg Med Chem 27: 1804-1817 (2019) Article DOI: 10.1016/j.bmc.2019.03.028
					More data for this Ligand-Target Pair