BDBM50524273 CHEMBL4447840

SMILES: CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1

InChI Key: InChIKey=HPAGFWZVTGGUPS-YZVOILCLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-1/beta type-5 (Homo sapiens (Human))	BDBM50524273 (CHEMBL4447840) Show SMILES CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1 |r| Show InChI InChI=1S/C19H34N2O5/c1-5-6-7-8-9-16(23)20-14(4)18(25)21-15(10-13(2)3)17(24)19(11-22)12-26-19/h13-15,22H,5-12H2,1-4H3,(H,20,23)(H,21,25)/t14-,15-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...				J Med Chem 62: 4444-4455 (2019) Article DOI: 10.1021/acs.jmedchem.8b01943
					More data for this Ligand-Target Pair
Proteasome subunit beta type-9 (Homo sapiens (Human))	BDBM50524273 (CHEMBL4447840) Show SMILES CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1 |r| Show InChI InChI=1S/C19H34N2O5/c1-5-6-7-8-9-16(23)20-14(4)18(25)21-15(10-13(2)3)17(24)19(11-22)12-26-19/h13-15,22H,5-12H2,1-4H3,(H,20,23)(H,21,25)/t14-,15-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...				J Med Chem 62: 4444-4455 (2019) Article DOI: 10.1021/acs.jmedchem.8b01943
					More data for this Ligand-Target Pair