BDBM50524375 CHEMBL4463811

SMILES: CC1CCCc2c1nc(N)nc2-c1ccc(Br)cc1

InChI Key: InChIKey=NWHOTUQSPOKGIZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524375 (CHEMBL4463811) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(Br)cc1 Show InChI InChI=1S/C15H16BrN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50524375 (CHEMBL4463811) Show SMILES CC1CCCc2c1nc(N)nc2-c1ccc(Br)cc1 Show InChI InChI=1S/C15H16BrN3/c1-9-3-2-4-12-13(9)18-15(17)19-14(12)10-5-7-11(16)8-6-10/h5-9H,2-4H2,1H3,(H2,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Scientific and Innovative Research (AcSIR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...				J Med Chem 62: 4638-4655 (2019) Article DOI: 10.1021/acs.jmedchem.9b00241
					More data for this Ligand-Target Pair