BDBM50524504 CHEMBL4440982

SMILES: FC(F)(F)C1(NC(Nc2ccccc2Br)=Nc2ccc(Cl)cc12)C#CC1CC1

InChI Key: InChIKey=REDZQXWKFVNPGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50524504 (CHEMBL4440982) Show SMILES FC(F)(F)C1(NC(Nc2ccccc2Br)=Nc2ccc(Cl)cc12)C#CC1CC1 |c:15| Show InChI InChI=1S/C20H14BrClF3N3/c21-15-3-1-2-4-17(15)27-18-26-16-8-7-13(22)11-14(16)19(28-18,20(23,24)25)10-9-12-5-6-12/h1-4,7-8,11-12H,5-6H2,(H2,26,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as te...				Eur J Med Chem 176: 11-20 (2019) Article DOI: 10.1016/j.ejmech.2019.05.011
					More data for this Ligand-Target Pair