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SMILES: Cc1ccsc1C(=O)n1cc(C(O)C2COC(=O)C2=C)c2cc(Cl)ccc12

InChI Key: InChIKey=PVBKFPNZJHROAE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524606   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM50524606
PNG
(CHEMBL4574897)
Show SMILES Cc1ccsc1C(=O)n1cc(C(O)C2COC(=O)C2=C)c2cc(Cl)ccc12
Show InChI InChI=1S/C20H16ClNO4S/c1-10-5-6-27-18(10)19(24)22-8-14(13-7-12(21)3-4-16(13)22)17(23)15-9-26-20(25)11(15)2/h3-8,15,17,23H,2,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Zhengzhou University

Curated by ChEMBL


Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ...

Eur J Med Chem 175: 357-372 (2019)


Article DOI: 10.1016/j.ejmech.2019.04.065
More data for this
Ligand-Target Pair