BDBM50526079 CHEMBL4454320

SMILES: FC(F)(F)c1ccnc(N2CCC(CC2)NC(=S)Nc2cccnc2)c1Cl

InChI Key: InChIKey=KDFLBIXMRJQZIL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50526079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD12 (Mus musculus)	BDBM50526079 (CHEMBL4454320) Show SMILES FC(F)(F)c1ccnc(N2CCC(CC2)NC(=S)Nc2cccnc2)c1Cl Show InChI InChI=1S/C17H17ClF3N5S/c18-14-13(17(19,20)21)3-7-23-15(14)26-8-4-11(5-9-26)24-16(27)25-12-2-1-6-22-10-12/h1-3,6-7,10-11H,4-5,8-9H2,(H2,24,25,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JJH350 binding to ABHD12 in mouse brain membrane proteome incubated for 20 mins by CuAAC fluorescence dependent gel-based competitive A...				J Med Chem 62: 1643-1656 (2019) Article DOI: 10.1021/acs.jmedchem.8b01958
					More data for this Ligand-Target Pair