BDBM50528194 CHEMBL4517408
SMILES: COc1cc(cc(OC)c1OC)-c1cncc(c1C)-c1ccc(cc1)N1CCNCC1
InChI Key: InChIKey=RKBYYWVZFBATHQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of TNIK (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of ALK2 G328V mutant (unknown origin) by radiometric assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK2 R206H mutant using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of ALK2 R258G mutant (unknown origin) by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl... | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 2.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of recombinant human ALK5 expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter after 24 hrs by dual ... | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 G328V mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na... | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 G356D mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na... | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 Q207D mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na... | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 R206H mutant (unknown origin) expressed in HEK293 cells incubated for 2 hrs by Na... | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Serine/threonine-protein kinase receptor R3 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bone morphogenetic protein receptor type-1A (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 428 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK3 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK4 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bone morphogenetic protein receptor type-1B (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK6 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of ABL1 (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine kinase 6 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of BRK (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of DDR1 (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Misshapen-like kinase 1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of MINK (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase NLK (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of NLK (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase SIK2 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of SIK2 (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 20 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of ZAK (unknown origin) | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of recombinant human CB1 incubated for 60 mins by scintillation counting method | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens) | BDBM50528194 (CHEMBL4517408) | PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 2.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of recombinant human adrenergic alpha2A receptor incubated for 60 mins by scintillation counting method | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae) | BDBM50528194 (CHEMBL4517408) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in HEK293 cells after 5 mins by IonWorks barracuda patch clamp method | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 20 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2B6 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate incubated for 20 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate incubated for 20 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate incubated for 20 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate incubated for 20 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 20 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | >9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 10 mins in presence of NADPH by LC/MS/MS analysis | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 2.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of human ALK5 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assay | J Med Chem 63: 10061-10085 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50528194 (CHEMBL4517408) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 | |||||||||||
More data for this Ligand-Target Pair |