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BDBM50528309 CHEMBL4588933

SMILES: ONC(=O)C(NC(=O)Cc1ccc(F)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1

InChI Key: InChIKey=GPTAMFPSOSMEJE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528309   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aminopeptidase


(Homo sapiens (Human))		BDBM50528309
PNG
(CHEMBL4588933)
Show SMILES ONC(=O)C(NC(=O)Cc1ccc(F)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1
Show InChI InChI=1S/C22H16F4N2O4/c23-15-6-1-11(7-18(15)29)8-19(30)27-21(22(31)28-32)13-4-2-12(3-5-13)14-9-16(24)20(26)17(25)10-14/h1-7,9-10,21,29,32H,8H2,(H,27,30)(H,28,31)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
 138n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...

J Med Chem 62: 7185-7209 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00757
More data for this
Ligand-Target Pair