BDBM50528926 CHEMBL4565200
SMILES: Cc1cc(C(N)=O)c(s1)-c1cccc(OC(=O)NCCN2CCN(CC2)c2ccccc2)c1
InChI Key: InChIKey=COGCORROFSOJTQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anandamide amidohydrolase (Mus musculus (mouse)) | BDBM50528926 (CHEMBL4565200) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of FAAH in mouse brain membranes assessed as inhibitory constant using [14C]-AEA as substrate incubated for 15 mins by scintillation count... | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50528926 (CHEMBL4565200) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Displacement of [3H]-spiperone from human D3 receptor expressed in CHO cells co-expressing Galpha16 incubated for 120 mins by liquid scintillation co... | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50528926 (CHEMBL4565200) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Displacement of [3H]-spiperone from human D3 receptor expressed in CHO cells co-expressing Galpha16 incubated for 120 mins by liquid scintillation co... | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50528926 (CHEMBL4565200) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Displacement of [3H]-spiperone from human D2 receptor expressed in CHO cells co-expressing Galpha16 incubated for 120 mins by liquid scintillation co... | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50528926 (CHEMBL4565200) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Displacement of [3H]-spiperone from human D2 receptor expressed in CHO cells co-expressing Galpha16 incubated for 120 mins by liquid scintillation co... | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae) | BDBM50528926 (CHEMBL4565200) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 282 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in HEK293 cells incubated for 72 hrs by patch clamp assay | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae) | BDBM50528926 (CHEMBL4565200) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in HEK293 cells incubated for 72 hrs by patch clamp assay | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anandamide amidohydrolase (Mus musculus (mouse)) | BDBM50528926 (CHEMBL4565200) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of FAAH in mouse brain membranes using [14C]-AEA as substrate incubated for 15 mins by scintillation counting method | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111674 | |||||||||||
More data for this Ligand-Target Pair |