BDBM50529383 CHEMBL4570334

SMILES: CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c(C)c(-c2cnn(C)c2)c1-c1cccc(F)c1

InChI Key: InChIKey=HCLROUKZVUKABY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50529383 (CHEMBL4570334) Show SMILES CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c(C)c(-c2cnn(C)c2)c1-c1cccc(F)c1 Show InChI InChI=1S/C24H21ClFN7/c1-13-19(25)8-18(14(2)32-24-22-23(28-11-27-22)29-12-30-24)21(15-5-4-6-17(26)7-15)20(13)16-9-31-33(3)10-16/h4-12,14H,1-3H3,(H2,27,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) using D-myophosphatidylinositol 4,5-bisphosphate as substrate incubated for 120 mins by [gamma-33P]ATP based...				ACS Med Chem Lett 10: 1554-1560 (2019) Article DOI: 10.1021/acsmedchemlett.9b00334
					More data for this Ligand-Target Pair