BDBM50529415 CHEMBL4588535

SMILES: CCC(=O)N(c1ccccc1)C1(CCN(CCc2cccc(O)c2)CC1)C(=O)OC

InChI Key: InChIKey=IZWWEXYFPQMWAZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50529415 (CHEMBL4588535) Show SMILES CCC(=O)N(c1ccccc1)C1(CCN(CCc2cccc(O)c2)CC1)C(=O)OC Show InChI InChI=1S/C24H30N2O4/c1-3-22(28)26(20-9-5-4-6-10-20)24(23(29)30-2)13-16-25(17-14-24)15-12-19-8-7-11-21(27)18-19/h4-11,18,27H,3,12-17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0140	n/a	n/a	n/a	n/a
United States Army CCDC Chemical Biological Center Curated by ChEMBL					Assay Description Agonist activity at human MOR expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins and measured after 1 hr by Eu-cAMP tracer...				ACS Med Chem Lett 10: 1568-1572 (2019) Article DOI: 10.1021/acsmedchemlett.9b00404
					More data for this Ligand-Target Pair