BDBM50529418 CHEMBL4452948

SMILES: Cc1cccc(C)c1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl

InChI Key: InChIKey=KJMZPIPMPOYAEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529418 (CHEMBL4452948) Show SMILES Cc1cccc(C)c1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C17H19ClN4O2/c1-11-4-3-5-12(2)13(11)9-22-7-6-21(10-15(22)23)14-8-19-20-17(24)16(14)18/h3-5,8H,6-7,9-10H2,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair