BDBM50529427 CHEMBL4536108

SMILES: C[C@H](N1CCN(CC1=O)c1cn[nH]c(=O)c1Cl)c1ccccc1C

InChI Key: InChIKey=GDKGPOWZYWWUSD-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529427 (CHEMBL4536108) Show SMILES C[C@H](N1CCN(CC1=O)c1cn[nH]c(=O)c1Cl)c1ccccc1C |r| Show InChI InChI=1S/C17H19ClN4O2/c1-11-5-3-4-6-13(11)12(2)22-8-7-21(10-15(22)23)14-9-19-20-17(24)16(14)18/h3-6,9,12H,7-8,10H2,1-2H3,(H,20,24)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair