BDBM50529452 CHEMBL4458885

SMILES: Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C1CC1

InChI Key: InChIKey=QJGWZUDPYWFSNL-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529452 (CHEMBL4458885) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C1CC1 Show InChI InChI=1S/C19H22N4O2/c1-13-4-2-3-5-15(13)11-23-9-8-22(12-17(23)24)16-10-20-21-19(25)18(16)14-6-7-14/h2-5,10,14H,6-9,11-12H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair