BDBM50529589 CHEMBL4239110

SMILES: C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O

InChI Key: InChIKey=UEWLDBXZCRMHEY-AAWHFPIWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50529589 (CHEMBL4239110) Show SMILES C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O Show InChI InChI=1S/C20H20O6/c1-12(11-21)2-6-15-18(24)9-7-16(20(15)26)17(23)8-4-13-3-5-14(22)10-19(13)25/h2-5,7-10,21-22,24-26H,6,11H2,1H3/b8-4+,12-2+	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin)				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529589 (CHEMBL4239110) Show SMILES C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O Show InChI InChI=1S/C20H20O6/c1-12(11-21)2-6-15-18(24)9-7-16(20(15)26)17(23)8-4-13-3-5-14(22)10-19(13)25/h2-5,7-10,21-22,24-26H,6,11H2,1H3/b8-4+,12-2+	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529589 (CHEMBL4239110) Show SMILES C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O Show InChI InChI=1S/C20H20O6/c1-12(11-21)2-6-15-18(24)9-7-16(20(15)26)17(23)8-4-13-3-5-14(22)10-19(13)25/h2-5,7-10,21-22,24-26H,6,11H2,1H3/b8-4+,12-2+	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50529589 (CHEMBL4239110) Show SMILES C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O Show InChI InChI=1S/C20H20O6/c1-12(11-21)2-6-15-18(24)9-7-16(20(15)26)17(23)8-4-13-3-5-14(22)10-19(13)25/h2-5,7-10,21-22,24-26H,6,11H2,1H3/b8-4+,12-2+	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase (unknown origin)				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967
					More data for this Ligand-Target Pair