BDBM50529771 CHEMBL4535267

SMILES: CCn1cc(cn1)-c1n[nH]c2cc(ccc12)-c1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=FQZREJPMQAXXHX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529771 (CHEMBL4535267) Show SMILES CCn1cc(cn1)-c1n[nH]c2cc(ccc12)-c1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O/c1-3-35-15-19(14-31-35)25-22-10-9-17(12-24(22)33-34-25)23-11-18(8-7-16(23)2)26(36)32-21-6-4-5-20(13-21)27(28,29)30/h4-15H,3H2,1-2H3,(H,32,36)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529771 (CHEMBL4535267) Show SMILES CCn1cc(cn1)-c1n[nH]c2cc(ccc12)-c1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O/c1-3-35-15-19(14-31-35)25-22-10-9-17(12-24(22)33-34-25)23-11-18(8-7-16(23)2)26(36)32-21-6-4-5-20(13-21)27(28,29)30/h4-15H,3H2,1-2H3,(H,32,36)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50529771 (CHEMBL4535267) Show SMILES CCn1cc(cn1)-c1n[nH]c2cc(ccc12)-c1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O/c1-3-35-15-19(14-31-35)25-22-10-9-17(12-24(22)33-34-25)23-11-18(8-7-16(23)2)26(36)32-21-6-4-5-20(13-21)27(28,29)30/h4-15H,3H2,1-2H3,(H,32,36)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50529771 (CHEMBL4535267) Show SMILES CCn1cc(cn1)-c1n[nH]c2cc(ccc12)-c1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O/c1-3-35-15-19(14-31-35)25-22-10-9-17(12-24(22)33-34-25)23-11-18(8-7-16(23)2)26(36)32-21-6-4-5-20(13-21)27(28,29)30/h4-15H,3H2,1-2H3,(H,32,36)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair