BDBM50529779 CHEMBL4525313

SMILES: Cc1ccc(cc1-c1ccc2cn[nH]c2c1)C(=O)Nc1cccc(c1)C(C)(C)C#N

InChI Key: InChIKey=JYBHWIJNMPVCGN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529779 (CHEMBL4525313) Show SMILES Cc1ccc(cc1-c1ccc2cn[nH]c2c1)C(=O)Nc1cccc(c1)C(C)(C)C#N Show InChI InChI=1S/C25H22N4O/c1-16-7-8-18(11-22(16)17-9-10-19-14-27-29-23(19)12-17)24(30)28-21-6-4-5-20(13-21)25(2,3)15-26/h4-14H,1-3H3,(H,27,29)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529779 (CHEMBL4525313) Show SMILES Cc1ccc(cc1-c1ccc2cn[nH]c2c1)C(=O)Nc1cccc(c1)C(C)(C)C#N Show InChI InChI=1S/C25H22N4O/c1-16-7-8-18(11-22(16)17-9-10-19-14-27-29-23(19)12-17)24(30)28-21-6-4-5-20(13-21)25(2,3)15-26/h4-14H,1-3H3,(H,27,29)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair