BDBM50529780 CHEMBL4448547

SMILES: Cc1ccc(cc1-c1ccc2cn[nH]c2c1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=OKFBUHWKHSSXLQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529780 (CHEMBL4448547) Show SMILES Cc1ccc(cc1-c1ccc2cn[nH]c2c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H16F3N3O/c1-13-5-6-15(9-19(13)14-7-8-16-12-26-28-20(16)10-14)21(29)27-18-4-2-3-17(11-18)22(23,24)25/h2-12H,1H3,(H,26,28)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529780 (CHEMBL4448547) Show SMILES Cc1ccc(cc1-c1ccc2cn[nH]c2c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H16F3N3O/c1-13-5-6-15(9-19(13)14-7-8-16-12-26-28-20(16)10-14)21(29)27-18-4-2-3-17(11-18)22(23,24)25/h2-12H,1H3,(H,26,28)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair