null

SMILES: CC(C)N1CCN(CC1)C(=O)c1nc(-c2ccc3N(C)C(=O)[C@@H](C)N(C4CCCC4)c3c2)n(n1)-c1ccc(C)cc1

InChI Key: InChIKey=ANSCAJONNBGMKJ-HSZRJFAPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50530512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50530512 (CHEMBL4518804 | US11078188, Example 15) Show SMILES CC(C)N1CCN(CC1)C(=O)c1nc(-c2ccc3N(C)C(=O)[C@@H](C)N(C4CCCC4)c3c2)n(n1)-c1ccc(C)cc1 |r| Show InChI InChI=1S/C32H41N7O2/c1-21(2)36-16-18-37(19-17-36)32(41)29-33-30(39(34-29)26-13-10-22(3)11-14-26)24-12-15-27-28(20-24)38(25-8-6-7-9-25)23(4)31(40)35(27)5/h10-15,20-21,23,25H,6-9,16-19H2,1-5H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of 5-FITC labelled (+)-JQ1 from His6-tagged human BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3) )-codon plus-RIL cells incu...				J Med Chem 62: 8642-8663 (2019) Article DOI: 10.1021/acs.jmedchem.9b01094
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50530512 (CHEMBL4518804 | US11078188, Example 15) Show SMILES CC(C)N1CCN(CC1)C(=O)c1nc(-c2ccc3N(C)C(=O)[C@@H](C)N(C4CCCC4)c3c2)n(n1)-c1ccc(C)cc1 |r| Show InChI InChI=1S/C32H41N7O2/c1-21(2)36-16-18-37(19-17-36)32(41)29-33-30(39(34-29)26-13-10-22(3)11-14-26)24-12-15-27-28(20-24)38(25-8-6-7-9-25)23(4)31(40)35(27)5/h10-15,20-21,23,25H,6-9,16-19H2,1-5H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50530512 (CHEMBL4518804 | US11078188, Example 15) Show SMILES CC(C)N1CCN(CC1)C(=O)c1nc(-c2ccc3N(C)C(=O)[C@@H](C)N(C4CCCC4)c3c2)n(n1)-c1ccc(C)cc1 |r| Show InChI InChI=1S/C32H41N7O2/c1-21(2)36-16-18-37(19-17-36)32(41)29-33-30(39(34-29)26-13-10-22(3)11-14-26)24-12-15-27-28(20-24)38(25-8-6-7-9-25)23(4)31(40)35(27)5/h10-15,20-21,23,25H,6-9,16-19H2,1-5H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of 5-FITC labelled (+)-JQ1 from His6-tagged human BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3) )-codon plus-RIL cells incu...				J Med Chem 62: 8642-8663 (2019) Article DOI: 10.1021/acs.jmedchem.9b01094
					More data for this Ligand-Target Pair