null

SMILES: Cc1nnc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)s1

InChI Key: InChIKey=GKQIAYLHELLDNZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50530668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530668 (CHEMBL4444451) Show SMILES Cc1nnc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)s1 Show InChI InChI=1S/C21H20FN7S2/c1-12-28-29-21(30-12)27-20-24-11-8-16(25-20)18-17(13-2-4-15(22)5-3-13)26-19(31-18)14-6-9-23-10-7-14/h2-5,8,11,14,23H,6-7,9-10H2,1H3,(H,24,25,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530668 (CHEMBL4444451) Show SMILES Cc1nnc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)s1 Show InChI InChI=1S/C21H20FN7S2/c1-12-28-29-21(30-12)27-20-24-11-8-16(25-20)18-17(13-2-4-15(22)5-3-13)26-19(31-18)14-6-9-23-10-7-14/h2-5,8,11,14,23H,6-7,9-10H2,1H3,(H,24,25,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099
					More data for this Ligand-Target Pair