BDBM50531238 CHEMBL4584910
SMILES: [H][C@]12CCC(=O)N1CC[C@@]1([H])Oc3cccc(C)c3C(=O)[C@]21[H]
InChI Key: InChIKey=OOLVDTFZFJPPGR-IXPVHAAZSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterases; ACHE & BCHE (Homo sapiens (Human)) | BDBM50531238 (CHEMBL4584910) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human erythrocyte BuChE using S-butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and meas... | J Nat Prod 82: 3221-3226 (2019) Article DOI: 10.1021/acs.jnatprod.8b01027 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterases; ACHE & BCHE (Homo sapiens (Human)) | BDBM50531238 (CHEMBL4584910) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human erythrocyte BuChE using S-butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and meas... | J Nat Prod 82: 3221-3226 (2019) Article DOI: 10.1021/acs.jnatprod.8b01027 | |||||||||||
More data for this Ligand-Target Pair |