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BDBM50531479 CHEMBL4439518

SMILES: ONC(=O)CCCCCn1cc(C(=O)Nc2nc3ccccc3s2)c(=O)c2ccccc12

InChI Key: InChIKey=YPISVXLJFVZZRI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50531479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyamine deacetylase HDAC10


(Mus musculus)		BDBM50531479
PNG
(CHEMBL4439518)
Show SMILES ONC(=O)CCCCCn1cc(C(=O)Nc2nc3ccccc3s2)c(=O)c2ccccc12
Show InChI InChI=1S/C23H22N4O4S/c28-20(26-31)12-2-1-7-13-27-14-16(21(29)15-8-3-5-10-18(15)27)22(30)25-23-24-17-9-4-6-11-19(17)32-23/h3-6,8-11,14,31H,1-2,7,12-13H2,(H,26,28)(H,24,25,30)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a



S£o Paulo State University (UNESP)

Curated by ChEMBL


Assay Description
Inhibition of mouse liver HDAC using Boc-Lys (Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins ...

Eur J Med Chem 164: 8-26 (2019)


Article DOI: 10.1016/j.ejmech.2018.12.033
More data for this
Ligand-Target Pair