BDBM50531751 CHEMBL4543212

SMILES: Cc1ccc(cc1)-c1cn(Cc2ccc(cc2)-c2cnn(C)c2)nn1

InChI Key: InChIKey=VZHPNWDSQYCLOK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50531751 (CHEMBL4543212) Show SMILES Cc1ccc(cc1)-c1cn(Cc2ccc(cc2)-c2cnn(C)c2)nn1 Show InChI InChI=1S/C20H19N5/c1-15-3-7-18(8-4-15)20-14-25(23-22-20)12-16-5-9-17(10-6-16)19-11-21-24(2)13-19/h3-11,13-14H,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
The First Affiliated Hospital of Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assay				Eur J Med Chem 164: 440-447 (2019) Article DOI: 10.1016/j.ejmech.2018.12.067
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2) (Homo sapiens (Human))	BDBM50531751 (CHEMBL4543212) Show SMILES Cc1ccc(cc1)-c1cn(Cc2ccc(cc2)-c2cnn(C)c2)nn1 Show InChI InChI=1S/C20H19N5/c1-15-3-7-18(8-4-15)20-14-25(23-22-20)12-16-5-9-17(10-6-16)19-11-21-24(2)13-19/h3-11,13-14H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
The First Affiliated Hospital of Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assay				Eur J Med Chem 164: 440-447 (2019) Article DOI: 10.1016/j.ejmech.2018.12.067
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50531751 (CHEMBL4543212) Show SMILES Cc1ccc(cc1)-c1cn(Cc2ccc(cc2)-c2cnn(C)c2)nn1 Show InChI InChI=1S/C20H19N5/c1-15-3-7-18(8-4-15)20-14-25(23-22-20)12-16-5-9-17(10-6-16)19-11-21-24(2)13-19/h3-11,13-14H,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
The First Affiliated Hospital of Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EphB4 (unknown origin) after 1 hrs by ADP-Glo luminescence assay				Eur J Med Chem 164: 440-447 (2019) Article DOI: 10.1016/j.ejmech.2018.12.067
					More data for this Ligand-Target Pair