BDBM50532012 CHEMBL4461542

SMILES: Cc1cc(NC(=O)Cn2nnc(n2)-c2cccc(F)c2)n(n1)C1CCCCC1

InChI Key: InChIKey=WHUCZPDJCNYDDS-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50532012 (CHEMBL4461542) Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2cccc(F)c2)n(n1)C1CCCCC1 Show InChI InChI=1S/C19H22FN7O/c1-13-10-17(27(23-13)16-8-3-2-4-9-16)21-18(28)12-26-24-19(22-25-26)14-6-5-7-15(20)11-14/h5-7,10-11,16H,2-4,8-9,12H2,1H3,(H,21,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	264	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50532012 (CHEMBL4461542) Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2cccc(F)c2)n(n1)C1CCCCC1 Show InChI InChI=1S/C19H22FN7O/c1-13-10-17(27(23-13)16-8-3-2-4-9-16)21-18(28)12-26-24-19(22-25-26)14-6-5-7-15(20)11-14/h5-7,10-11,16H,2-4,8-9,12H2,1H3,(H,21,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair