BDBM50532045 CHEMBL4529550

SMILES: Cc1cc(NC(=O)Cn2nnc(n2)-c2ccc(C)cc2)n(n1)C1CCCCC1

InChI Key: InChIKey=GOYARANKDHAVHB-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50532045 (CHEMBL4529550) Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2ccc(C)cc2)n(n1)C1CCCCC1 Show InChI InChI=1S/C20H25N7O/c1-14-8-10-16(11-9-14)20-22-25-26(24-20)13-19(28)21-18-12-15(2)23-27(18)17-6-4-3-5-7-17/h8-12,17H,3-7,13H2,1-2H3,(H,21,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	408	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50532045 (CHEMBL4529550) Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2ccc(C)cc2)n(n1)C1CCCCC1 Show InChI InChI=1S/C20H25N7O/c1-14-8-10-16(11-9-14)20-22-25-26(24-20)13-19(28)21-18-12-15(2)23-27(18)17-6-4-3-5-7-17/h8-12,17H,3-7,13H2,1-2H3,(H,21,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	111	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair