BDBM50532145 CHEMBL1549559

SMILES: Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1

InChI Key: InChIKey=TYHXOVYFQAXETR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50532145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50532145 (CHEMBL1549559) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1 Show InChI InChI=1S/C17H16N4O4S2/c1-13-3-7-15(8-4-13)26(22,23)20-14-5-9-16(10-6-14)27(24,25)21-17-18-11-2-12-19-17/h2-12,20H,1H3,(H,18,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 27: 1009-1022 (2019) Article DOI: 10.1016/j.bmc.2019.01.043
					More data for this Ligand-Target Pair