BDBM50532167 CHEMBL4460961

SMILES: Cc1ccc2nc(cc(C(=O)OCc3ccccc3)c2c1)-c1ccc(F)cc1

InChI Key: InChIKey=JWSCZDUDYWOXND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50532167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM50532167 (CHEMBL4460961) Show SMILES Cc1ccc2nc(cc(C(=O)OCc3ccccc3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H18FNO2/c1-16-7-12-22-20(13-16)21(24(27)28-15-17-5-3-2-4-6-17)14-23(26-22)18-8-10-19(25)11-9-18/h2-14H,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal His-tagged DHODH (31 to 395 residues) expressed in Escherichia coli using DHO as substrate measured after ...				Bioorg Med Chem Lett 29: 917-922 (2019) Article DOI: 10.1016/j.bmcl.2019.01.038
					More data for this Ligand-Target Pair