null

SMILES: O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1

InChI Key: InChIKey=DOQSCHLSVSXYAQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50532434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	184	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	184	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 catalytic site preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 catalytic site preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50532434 (CHEMBL4460933) Show SMILES O=C(Nc1cccc2c1C(=O)NS2(=O)=O)c1ccccc1 Show InChI InChI=1S/C14H10N2O4S/c17-13(9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)14(18)16-21(11,19)20/h1-8H,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				J Med Chem 59: 6547-52 (2016) Article DOI: 10.1021/acs.jmedchem.6b00616
					More data for this Ligand-Target Pair