BDBM50532867 CHEMBL4518126

SMILES: Cl.C[C@H](N)C(=O)NCc1ccc(Oc2ccc(F)cc2)c(C)c1

InChI Key: InChIKey=IKCROSXEEYQDIR-YDALLXLXSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50532867 (CHEMBL4518126) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2ccc(F)cc2)c(C)c1 |r| Show InChI InChI=1S/C17H19FN2O2.ClH/c1-11-9-13(10-20-17(21)12(2)19)3-8-16(11)22-15-6-4-14(18)5-7-15;/h3-9,12H,10,19H2,1-2H3,(H,20,21);1H/t12-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of PRMT6 (unknown origin)				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50532867 (CHEMBL4518126) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2ccc(F)cc2)c(C)c1 |r| Show InChI InChI=1S/C17H19FN2O2.ClH/c1-11-9-13(10-20-17(21)12(2)19)3-8-16(11)22-15-6-4-14(18)5-7-15;/h3-9,12H,10,19H2,1-2H3,(H,20,21);1H/t12-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of PRMT6 (unknown origin)				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50532867 (CHEMBL4518126) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2ccc(F)cc2)c(C)c1 |r| Show InChI InChI=1S/C17H19FN2O2.ClH/c1-11-9-13(10-20-17(21)12(2)19)3-8-16(11)22-15-6-4-14(18)5-7-15;/h3-9,12H,10,19H2,1-2H3,(H,20,21);1H/t12-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50532867 (CHEMBL4518126) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2ccc(F)cc2)c(C)c1 |r| Show InChI InChI=1S/C17H19FN2O2.ClH/c1-11-9-13(10-20-17(21)12(2)19)3-8-16(11)22-15-6-4-14(18)5-7-15;/h3-9,12H,10,19H2,1-2H3,(H,20,21);1H/t12-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair