BDBM50532876 CHEMBL4576510

SMILES: CC(N)C(=O)NCc1ccc(Oc2ccccc2F)c(F)c1

InChI Key: InChIKey=WPEOYQUVJYOMDY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50532876 (CHEMBL4576510) Show SMILES CC(N)C(=O)NCc1ccc(Oc2ccccc2F)c(F)c1 Show InChI InChI=1S/C16H16F2N2O2/c1-10(19)16(21)20-9-11-6-7-15(13(18)8-11)22-14-5-3-2-4-12(14)17/h2-8,10H,9,19H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50532876 (CHEMBL4576510) Show SMILES CC(N)C(=O)NCc1ccc(Oc2ccccc2F)c(F)c1 Show InChI InChI=1S/C16H16F2N2O2/c1-10(19)16(21)20-9-11-6-7-15(13(18)8-11)22-14-5-3-2-4-12(14)17/h2-8,10H,9,19H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of PRMT6 (unknown origin)				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50532876 (CHEMBL4576510) Show SMILES CC(N)C(=O)NCc1ccc(Oc2ccccc2F)c(F)c1 Show InChI InChI=1S/C16H16F2N2O2/c1-10(19)16(21)20-9-11-6-7-15(13(18)8-11)22-14-5-3-2-4-12(14)17/h2-8,10H,9,19H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of PRMT6 (unknown origin)				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50532876 (CHEMBL4576510) Show SMILES CC(N)C(=O)NCc1ccc(Oc2ccccc2F)c(F)c1 Show InChI InChI=1S/C16H16F2N2O2/c1-10(19)16(21)20-9-11-6-7-15(13(18)8-11)22-14-5-3-2-4-12(14)17/h2-8,10H,9,19H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair