BDBM50534650 CHEMBL4593826

SMILES: COP(=O)(Nc1nc(sc1C(O)=O)-c1ccc(cc1)-c1cc2nccc(N)n2n1)c1ccc(C)cc1C

InChI Key: InChIKey=CFGKBMKFQCQTCD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50534650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV))	BDBM50534650 (CHEMBL4593826) Show SMILES COP(=O)(Nc1nc(sc1C(O)=O)-c1ccc(cc1)-c1cc2nccc(N)n2n1)c1ccc(C)cc1C Show InChI InChI=1S/C25H23N6O4PS/c1-14-4-9-19(15(2)12-14)36(34,35-3)30-23-22(25(32)33)37-24(28-23)17-7-5-16(6-8-17)18-13-21-27-11-10-20(26)31(21)29-18/h4-13H,26H2,1-3H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Idenix SARL, an MSD Company Curated by ChEMBL					Assay Description Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 26: 4536-4541 (2016) Article DOI: 10.1016/j.bmcl.2016.01.042
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50534650 (CHEMBL4593826) Show SMILES COP(=O)(Nc1nc(sc1C(O)=O)-c1ccc(cc1)-c1cc2nccc(N)n2n1)c1ccc(C)cc1C Show InChI InChI=1S/C25H23N6O4PS/c1-14-4-9-19(15(2)12-14)36(34,35-3)30-23-22(25(32)33)37-24(28-23)17-7-5-16(6-8-17)18-13-21-27-11-10-20(26)31(21)29-18/h4-13H,26H2,1-3H3,(H,30,34)(H,32,33)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	337	n/a	n/a	n/a	n/a	n/a	n/a
Idenix SARL, an MSD Company Curated by ChEMBL					Assay Description Inhibition of HCV genotype 2a JFH NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 26: 4536-4541 (2016) Article DOI: 10.1016/j.bmcl.2016.01.042
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM50534650 (CHEMBL4593826) Show SMILES COP(=O)(Nc1nc(sc1C(O)=O)-c1ccc(cc1)-c1cc2nccc(N)n2n1)c1ccc(C)cc1C Show InChI InChI=1S/C25H23N6O4PS/c1-14-4-9-19(15(2)12-14)36(34,35-3)30-23-22(25(32)33)37-24(28-23)17-7-5-16(6-8-17)18-13-21-27-11-10-20(26)31(21)29-18/h4-13H,26H2,1-3H3,(H,30,34)(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Idenix SARL, an MSD Company Curated by ChEMBL					Assay Description Inhibition of HCV genotype 3a NZL1 NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 26: 4536-4541 (2016) Article DOI: 10.1016/j.bmcl.2016.01.042
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50534650 (CHEMBL4593826) Show SMILES COP(=O)(Nc1nc(sc1C(O)=O)-c1ccc(cc1)-c1cc2nccc(N)n2n1)c1ccc(C)cc1C Show InChI InChI=1S/C25H23N6O4PS/c1-14-4-9-19(15(2)12-14)36(34,35-3)30-23-22(25(32)33)37-24(28-23)17-7-5-16(6-8-17)18-13-21-27-11-10-20(26)31(21)29-18/h4-13H,26H2,1-3H3,(H,30,34)(H,32,33)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Idenix SARL, an MSD Company Curated by ChEMBL					Assay Description Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 26: 4536-4541 (2016) Article DOI: 10.1016/j.bmcl.2016.01.042
					More data for this Ligand-Target Pair