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SMILES: NC(=O)c1cccc(c1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1

InChI Key: InChIKey=GJHTUHJCNMZSFF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534865   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM50534865
PNG
(CHEMBL4455319)
Show SMILES NC(=O)c1cccc(c1)-c1ccc(CNS(=O)(=O)c2cc3ccccc3[nH]2)cc1
Show InChI InChI=1S/C22H19N3O3S/c23-22(26)19-6-3-5-17(12-19)16-10-8-15(9-11-16)14-24-29(27,28)21-13-18-4-1-2-7-20(18)25-21/h1-13,24-25H,14H2,(H2,23,26)
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n/an/a 300n/an/an/an/an/an/a



University of Aberdeen

Curated by ChEMBL


Assay Description
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment pr...

Bioorg Med Chem Lett 26: 4403-4407 (2016)


Article DOI: 10.1016/j.bmcl.2016.08.018
BindingDB Entry DOI: 10.7270/Q2P84GD8
More data for this
Ligand-Target Pair