BDBM50535441 CHEMBL4461490

SMILES: CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccc(cc2)C#N)cc1)C(O)=O

InChI Key: InChIKey=VOSOHADSHGYQNQ-BYYHNAKLSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50535441 (CHEMBL4461490) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccc(cc2)C#N)cc1)C(O)=O Show InChI InChI=1S/C25H23N3O4/c1-25(2,24(29)30)32-23-11-5-18(6-12-23)15-16-31-22-13-9-21(10-14-22)28-27-20-7-3-19(17-26)4-8-20/h3-14H,15-16H2,1-2H3,(H,29,30)/b28-27+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a
University of Chieti "G. d.Annunzio" Curated by ChEMBL					Assay Description Transactivation of GAL4-tagged human PPARdelta LBD expressed in human HepG2 cells at 100 nM to 100 uM incubated for 20 to 22 hrs by luciferase report...				ACS Med Chem Lett 10: 545-551 (2019) Article DOI: 10.1021/acsmedchemlett.8b00574
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50535441 (CHEMBL4461490) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccc(cc2)C#N)cc1)C(O)=O Show InChI InChI=1S/C25H23N3O4/c1-25(2,24(29)30)32-23-11-5-18(6-12-23)15-16-31-22-13-9-21(10-14-22)28-27-20-7-3-19(17-26)4-8-20/h3-14H,15-16H2,1-2H3,(H,29,30)/b28-27+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
University of Chieti "G. d.Annunzio" Curated by ChEMBL					Assay Description Transactivation of GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells at 100 nM to 100 uM incubated for 20 to 22 hrs by luciferase report...				ACS Med Chem Lett 10: 545-551 (2019) Article DOI: 10.1021/acsmedchemlett.8b00574
					More data for this Ligand-Target Pair