BDBM50535478 CHEMBL4459681

SMILES: CC(C)[C@H](N)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N

InChI Key: InChIKey=XFELEBVIAJZIEI-ZDUSSCGKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
T1R2/T1R3 (Homo sapiens (Human))	BDBM50535478 (CHEMBL4459681) Show SMILES CC(C)[C@H](N)C(=O)NCc1ccc(o1)-c1cncc(C(O)=O)c1N |r| Show InChI InChI=1S/C16H20N4O4/c1-8(2)13(17)15(21)20-5-9-3-4-12(24-9)10-6-19-7-11(14(10)18)16(22)23/h3-4,6-8,13H,5,17H2,1-2H3,(H2,18,19)(H,20,21)(H,22,23)/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.46E+7	n/a	n/a	n/a	n/a
Ajinomoto Co., Inc. Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calc...				ACS Med Chem Lett 10: 800-805 (2019) Article DOI: 10.1021/acsmedchemlett.9b00051
					More data for this Ligand-Target Pair