null
SMILES: COc1cc(OCc2cccc(c2C)-c2cccc(COc3ccc(CN[C@H](CO)C(O)=O)c(OCc4cncc(c4)C#N)c3)c2C)ccc1CN[C@H](CO)C(O)=O
InChI Key: InChIKey=RHTFKMFRAYRFAI-XRSDMRJBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand/protein 1 (Homo sapiens-Homo sapiens (Human)) | BDBM50535765 (CHEMBL4578475) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ... | Bioorg Med Chem Lett 29: 2464-2467 (2019) Article DOI: 10.1016/j.bmcl.2019.07.027 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death 1 ligand 1 (Homo sapiens (Human)) | BDBM50535765 (CHEMBL4578475) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Binding affinity to FC-tagged human PDL1 by SPR assay | Bioorg Med Chem Lett 29: 2464-2467 (2019) Article DOI: 10.1016/j.bmcl.2019.07.027 | |||||||||||
More data for this Ligand-Target Pair |