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SMILES: CC(c1cc2cccnc2cc1C)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1

InChI Key: InChIKey=DONFIWAAXBRKAI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536480   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536480
PNG
(CHEMBL4568802)
Show SMILES CC(c1cc2cccnc2cc1C)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1
Show InChI InChI=1S/C24H19FN6O/c1-13-8-20-15(4-3-7-27-20)9-18(13)14(2)31-12-29-23-24(31)30-21(11-28-23)16-5-6-17(22(26)32)19(25)10-16/h3-12,14H,1-2H3,(H2,26,32)
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KEGG

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PubMed
n/an/an/an/a 12n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair