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SMILES: CC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnc2ccccc2c1

InChI Key: InChIKey=OOFBFLMNYYNTSA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536481   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50536481
PNG
(CHEMBL4566100)
Show SMILES CC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnc2ccccc2c1
Show InChI InChI=1S/C25H17FN6/c1-15(19-10-17-6-4-8-27-22(17)11-20(19)26)32-14-30-24-25(32)31-23(13-29-24)18-9-16-5-2-3-7-21(16)28-12-18/h2-15H,1H3
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PC cid
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PubMed
n/an/an/an/a 3.40n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...

Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
More data for this
Ligand-Target Pair